Appendix 6: Randomized Controlled Trials of Cryotherapy for the Prevention of Oral Mucositis in Adult and Pediatric Patients Receiving Treatment for Cancer or Undergoing Hematopoietic Stem Cell Transplantation – Outcomes
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چکیده
Salvador (2012) [2] Cryotherapy versus no cryotherapy 23 22 Overall mean (SE) of oral mucositis severity for the cryotherapy arm significantly lower than that for the control group: 0.43 (0.12) vs 1.14 (0.12); P<0.001 on a 0-4 scale Overall mean (SE) mucositis-related pain score for the cryotherapy arm significantly lower than that for the control group: 0.30 (0.23) vs 1.64 (0.24); P < 0.001 on a 0-10 scale Four participants experienced teeth sensitivity and complained of chills during cryotherapy, did not deter completion of therapy
منابع مشابه
Efficacy of Oral Cryotherapy on Oral Mucositis Prevention in Patients with Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplantation: A Meta-Analysis of Randomized Controlled Trials
OBJECTIVES Controversy exists regarding whether oral cryotherapy can prevent oral mucositis (OM) in patients with hematological malignancies undergoing hematopoietic stem cell transplantation (HSCT). The aim of the present meta-analysis was to evaluate the efficacy of oral cryotherapy for OM prevention in patients with hematological malignancies undergoing HSCT. METHODS PubMed and the Cochran...
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PURPOSE To develop an evidence-based clinical practice guideline for the prevention of oral mucositis in children (0-18 years) receiving treatment for cancer or undergoing haematopoietic stem cell transplantation (HSCT). METHODS The Mucositis Prevention Guideline Development Group was interdisciplinary and included internationally recognised experts in paediatric mucositis. For the evidence r...
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The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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